Amyloidosis

What is it?
Amyloidosis is a condition where abnormal protein (amyloid) builds up in various parts of the body.  When amyloid accumulates in the larynx, dysphonia, dysphagia (trouble swallowing), or dyspnea (shortness of breath) can result.  Particularly troublesome for voice production is amyloid that builds up on the vocal folds, limiting the ability to generate the wave necessary for voice production.

How is it treated?
Amyloidosis should be managed primarily by a specialist in the disorder, often an hematologist/oncologist, but may include a number of specialists based on the organs affected.  Accumulations in the upper aerodigestive tract, larynx, or trachea can be removed surgically based on patient symptoms.